Category: Books (Page 1 of 10)

A powerful memoir from Katalin Karikó, winner of the 2023 Nobel Prize in Physiology or Medicine, whose decades-long research led to the COVID-19 vaccines

“Katalin Karikó’s story is an inspiration.”—Bill Gates

“Riveting . . . a true story of a brilliant biochemist who never gave up or gave in.”—Bonnie Garmus, author of Lessons in Chemistry

A KIRKUS REVIEWS BEST BOOK OF THE YEAR

Katalin Karikó has had an unlikely journey. The daughter of a butcher in postwar communist Hungary, Karikó grew up in an adobe home that lacked running water, and her family grew their own vegetables. She saw the wonders of nature all around her and was determined to become a scientist. That determination eventually brought her to the United States, where she arrived as a postdoctoral fellow in 1985 with $1,200 sewn into her toddler’s teddy bear and a dream to remake medicine.

Karikó worked in obscurity, battled cockroaches in a windowless lab, and faced outright derision and even deportation threats from her bosses and colleagues. She balked as prestigious research institutions increasingly conflated science and money. Despite setbacks, she never wavered in her belief that an ephemeral and underappreciated molecule called messenger RNA could change the world. Karikó believed that someday mRNA would transform ordinary cells into tiny factories capable of producing their own medicines on demand. She sacrificed nearly everything for this dream, but the obstacles she faced only motivated her, and eventually she succeeded.

Karikó’s three-decade-long investigation into mRNA would lead to a staggering achievement: vaccines that protected millions of people from the most dire consequences of COVID-19. These vaccines are just the beginning of mRNA’s potential. Today, the medical community eagerly awaits more mRNA vaccines—for the flu, HIV, and other emerging infectious diseases.

Breaking Through isn’t just the story of an extraordinary woman. It’s an indictment of closed-minded thinking and a testament to one woman’s commitment to laboring intensely in obscurity—knowing she might never be recognized in a culture that is driven by prestige, power, and privilege—because she believed her work would save lives.

An Instant New York Times Bestseller

“A knockout collection. … Sharp-edged satire deceptively wrapped like a box of Neuhaus chocolates, Table for Two is a winner.” —The New York Times

“Superb … This may be Towles’ best book yet. Each tale is as satisfying as a master chef’s main course, filled with drama, wit, erudition and, most of all, heart.” —Los Angeles Times

Millions of Amor Towles fans are in for a treat as he shares some of his shorter fiction: six stories based in New York City and a novella set in Golden Age Hollywood.

The New York stories, most of which take place around the year 2000, consider the fateful consequences that can spring from brief encounters and the delicate mechanics of compromise that operate at the heart of modern marriages.

In Towles’s novel Rules of Civility, the indomitable Evelyn Ross leaves New York City in September 1938 with the intention of returning home to Indiana. But as her train pulls into Chicago, where her parents are waiting, she instead extends her ticket to Los Angeles. Told from seven points of view, “Eve in Hollywood” describes how Eve crafts a new future for herself—and others—in a noirish tale that takes us through the movie sets, bungalows, and dive bars of Los Angeles.

Written with his signature wit, humor, and sophistication, Table for Two is another glittering addition to Towles’s canon of stylish and transporting fiction.

“A sixty-year saga of frostbite and fake news that follows the no-holds-barred battle between two legendary explorers to reach the North Pole, and the newspapers which stopped at nothing to get–and sell–the story. In the fall of 1909, a pair of bitter contests captured the world’s attention. The American explorers Robert Peary and Frederick Cook both claimed to have discovered the North Pole, sparking a vicious feud that was unprecedented in international scientific and geographic circles. At the same time, the rivalry between two powerful New York City newspapers–the storied Herald and the ascendant Times–fanned the flames of the so-called polar controversy, as each paper financially and reputationally committed itself to an opposing explorer and fought desperately to defend him. The Herald was owned and edited by James Gordon Bennett, Jr., an eccentric playboy whose nose for news was matched only by his appetite for debauchery and champagne. The Times was published by Adolph Ochs, son of Jewish immigrants, who’d improbably rescued the paper from extinction and turned it into an emerging powerhouse. The battle between Cook and Peary would have enormous consequences for both newspapers, and help to determine the future of corporate media. Battle of Ink and Ice presents a frank portrayal of Arctic explorers, brave men who both inspired and divided the public. It also sketches a vivid portrait of the newspapers that funded, promoted, narrated, and often distorted their exploits. It recounts a sixty-year saga of frostbite and fake news, one that culminates with an unjustly overlooked chapter in the origin story of the modern New York Times. By turns tragic and absurd, Battle of Ink and Ice brims with contemporary relevance, touching as it does on themes of class, celebrity, the ever-quickening news cycle, and the benefits and pitfalls of an increasingly interconnected world. Above all, perhaps, its cast of characters testifies–colorfully and compellingly–to the ongoing role of personality and publicity in American cultural life as the Gilded Age gave way to the twentieth century–the American century”–

“A story of perseverance and the power of convictions from the groundbreaking immigrant scientist whose decades-long research led to the COVID-19 vaccines. Katalin Karikó had an unlikely journey. The daughter of a butcher in postwar communist Hungary, Karikó grew up in a one-room home that lacked running water, and her family grew their own vegetables. She saw the wonders of nature all around her and was determined to become a scientist. That determination eventually brought her to the United States, where she arrived as a postdoctoral fellow in 1985 with $1,200 sewn into her toddler’s teddy bear and a dream to remake medicine. Karikó worked in obscurity, battled cockroaches in a windowless lab, and faced outright derision and even deportation threats from her bosses and colleagues. She balked as prestigious research institutions increasingly conflated science and money. Despite setbacks, she never wavered in her belief that an ephemeral and underappreciated molecule called messenger RNA could change the world. Karikó believed that someday mRNA would transform ordinary cells into tiny factories capable of producing their own medicines on demand. She sacrificed nearly everything for this dream, but the obstacles she faced only motivated her, and eventually she succeeded. Karikó’s three-decades-long investigation into mRNA would lead to a staggering achievement: vaccines that protected millions of people from the most dire consequences of COVID-19. These vaccines are just the beginning of mRNA’s potential. Today, the medical community eagerly awaits more mRNA vaccines-for the flu, HIV, and other emerging infectious diseases. Breaking Through isn’t just the story of an extraordinary woman-it’s an indictment of closed-minded thinking and a testament to one woman’s commitment to laboring intensely in obscurity-knowing she might never be recognized in a culture that is more driven by prestige, power, and privilege-because she believed her work would save lives”–

“The millions of readers of Amor Towles are in for a treat as he shares some of his shorter fiction: six stories set in New York City and a novella in Los Angeles. The New York stories, most of which are set around the turn of the millennium, take up everything from the death-defying acrobatics of the male ego, to the fateful consequences of brief encounters, and the delicate mechanics of comprise which operate at the heart of modern marriages. In Towles’s novel, Rules of Civility, the indomitable Evelyn Ross leaves New York City in September, 1938, with the intention of returning home to Indiana. But as her train pulls into Chicago, where her parents are waiting, she instead extends her ticket to Los Angeles. Told from seven points of view, “Eve in Hollywood” describes how Eve crafts a new future for herself-and others-in the midst of Hollywood’s golden age. Throughout the stories, two characters often find themselves sitting across a table for two where the direction of their futures may hinge upon what they say to each other next. Written with his signature wit, humor, and sophistication, Table for Two is another glittering addition to Towles’s canon of stylish and transporting historical fiction”–

On November 6, 1860, Abraham Lincoln became the fluky victor in a tight race for president. The country was bitterly at odds; Southern extremists were moving ever closer to destroying the Union, with one state after another seceding and Lincoln powerless to stop them. Slavery fueled the conflict, but somehow the passions of North and South came to focus on a lonely federal fortress in Charleston Harbor: Fort Sumter.

Master storyteller Erik Larson offers a gripping account of the chaotic months between Lincoln’s election and the Confederacy’s shelling of Sumter—a period marked by tragic errors and miscommunications, enflamed egos and craven ambitions, personal tragedies and betrayals. Lincoln himself wrote that the trials of these five months were “so great that, could I have anticipated them, I would not have believed it possible to survive them.”

At the heart of this suspense-filled narrative are Major Robert Anderson, Sumter’s commander and a former slave owner sympathetic to the South but loyal to the Union; Edmund Ruffin, a vain and bloodthirsty radical who stirs secessionist ardor at every opportunity; and Mary Boykin Chesnut, wife of a prominent planter, conflicted over both marriage and slavery and seeing parallels between them. In the middle of it all is the overwhelmed Lincoln, battling with his duplicitous secretary of state, William Seward, as he tries desperately to avert a war that he fears is inevitable—one that will eventually kill 750,000 Americans.

Drawing on diaries, secret communiques, slave ledgers, and plantation records, Larson gives us a political horror story that captures the forces that led America to the brink—a dark reminder that we often don’t see a cataclysm coming until it’s too late.

“China’s economy has been booming for decades now. Keyu Jin, an economist who was born in China and educated in the United States, brings her fluency in Eastern and Western cultures together to offer an explanation of how China became such a successful economic story. This book is a guide to the Chinese economy as it has shifted from being based primarily on state-owned enterprise to being based on entrepreneurship and participation in the global economy”–

Alexander von Humboldt (1769-1859) was an intrepid explorer and the most famous scientist of his age. His restless life was packed with adventure and discovery, whether climbing the highest volcanoes in the world or racing through anthrax-infested Siberia. He came up with a radical vision of nature, that it was a complex and interconnected global force and did not exist for man’s use alone. Ironically, his ideas have become so accepted and widespread that he has been nearly forgotten.

Now Andrea Wulf brings the man and his achievements back into focus: his investigation of wild environments around the world; his discoveries of similarities between climate zones on different continents; his prediction of human-induced climate change; his remarkable ability to fashion poetic narrative out of scientific observation; and his relationships with iconic figures such as Simón Bolívar and Thomas Jefferson. Wulf examines how his writings inspired other naturalists and poets such as Wordsworth, Darwin, and Goethe, and she makes the compelling case that it was Humboldt’s influence on John Muir that led him to his ideas of preservation and that shaped Thoreau’s Walden.

Humboldt was the most interdisciplinary of scientists and is the forgotten father of environmentalism. With this brilliantly researched and compellingly written audiobook, she makes clear the myriad, fundamental ways that Humboldt created our understanding of the natural world.

“An epic account of the decades-long battle to control what has emerged as the world’s most critical resource–microchip technology–with the United States and China increasingly in conflict. You may be surprised to learn that microchips are the new oil–the scarce resource on which the modern world depends. Today, military, economic, and geopolitical power are built on a foundation of computer chips. Virtually everything–from missiles to microwaves, smartphones to the stock market–runs on chips. Until recently, America designed and built the fastest chips and maintained its lead as the #1 superpower. Now, America’s edge is slipping, undermined by competitors in Taiwan, Korea, Europe, and, above all, China. Today, as Chip War reveals, China, which spends more money each year importing chips than it spends importing oil, is pouring billions into a chip-building initiative to catch up to the US. At stake is America’s military superiority and economic prosperity. Economic historian Chris Miller explains how the semiconductor came to play a critical role in modern life and how the U.S. become dominant in chip design and manufacturing and applied this technology to military systems. America’s victory in the Cold War and its global military dominance stems from its ability to harness computing power more effectively than any other power. But here, too, China is catching up, with its chip-building ambitions and military modernization going hand in hand. America has let key components of the chip-building process slip out of its grasp, contributing not only to a worldwide chip shortage but also a new Cold War with a superpower adversary that is desperate to bridge the gap. Illuminating, timely, and fascinating, Chip War shows that, to make sense of the current state of politics, economics, and technology, we must first understand the vital role played by chips”–Amazon.